肾移植后发生的1例罕见的爱泼斯坦-巴尔病毒相关肝脾平滑肌肿瘤
A rare case of Epstein-Barr virus-associated hepatosplenic smooth muscle tumors after kidney transplantation.
作者信息
Pircher C, Schneeberger S, Boesmueller C, Agaimy A, Zoller H, Bale R, Henninger B, Mayer G, Neuwirt H
机构信息
Department of Internal Medicine IV, Nephrology and Hypertension, Medical University of Innsbruck, Innsbruck, Austria.
Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
出版信息
Transpl Infect Dis. 2018 Jun;20(3):e12860. doi: 10.1111/tid.12860. Epub 2018 Mar 3.
A 27-year old caucasian male was diagnosed 2.7 years after kidney transplantation with Epstein-Barr virus (EBV)-associated smooth muscle tumors in liver and spleen. The reduction in immunosuppression and conversion from tacrolimus to sirolimus did not lead to a regression of the tumors. Additionally, the patient developed a cellular rejection of his renal allograft, which was successfully treated. A combined approach with stereotactic radiofrequency ablation (SRFA) and surgical resection was effective in the treatment of the tumors.
一名27岁的白种男性在肾移植2.7年后被诊断出肝脏和脾脏患有与爱泼斯坦-巴尔病毒（EBV）相关的平滑肌瘤。免疫抑制的减少以及从他克莫司转换为西罗莫司并未导致肿瘤消退。此外，该患者发生了肾移植的细胞排斥反应，经治疗成功。立体定向射频消融（SRFA）与手术切除相结合的方法对肿瘤治疗有效。
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