皮损磨削术后面部增生性瘢痕和瘢痕疙瘩的皮损内注射5-氟尿嘧啶治疗

Treatment of postdermabrasion facial hypertrophic and keloid scars with intralesional 5-Fluorouracil injections.

作者信息

Goldan O, Weissman O, Regev E, Haik J, Winkler E

机构信息

Department of Plastic and Reconstructive Surgery, Sheba Medical Center, Tel-hashomer (affiliated with Sackler School of Medicine, Tel-Aviv University, Israel), Ramat Gan 52620, Israel.

出版信息

Aesthetic Plast Surg. 2008 Mar;32(2):389-92. doi: 10.1007/s00266-007-9109-3.

DOI:10.1007/s00266-007-9109-3

PMID:18185952

Abstract

Hypertrophic and keloid scarring is a known complication of dermabrasion facial resurfacing, although only a very small fraction of patients experience it. Treatment with intralesional corticosteroid injections and flashed pumped vascular dye laser is recommended in the literature. The treatment of keloid and hypertrophic scars using intralesional 5-fluorouracil (5-FU) injections has been well described, but there is no literature regarding use of the same treatment for postdermabrasion hypertrophic and keloid scars. In this case report, we describe a 67-year-old woman with persistent postdermabrasion facial hypertrophic and keloid scars that were treated at our scar clinic using intralesional 5-FU injections.

摘要

肥厚性瘢痕和瘢痕疙瘩是面部磨皮换肤术已知的并发症，尽管只有极少数患者会出现这种情况。文献推荐使用病灶内注射皮质类固醇和闪光灯泵浦血管染料激光进行治疗。病灶内注射5-氟尿嘧啶（5-FU）治疗瘢痕疙瘩和肥厚性瘢痕已有详尽描述，但尚无关于将同样的治疗方法用于磨皮术后肥厚性瘢痕和瘢痕疙瘩的文献。在本病例报告中，我们描述了一名67岁女性，她面部存在磨皮术后持续的肥厚性瘢痕和瘢痕疙瘩，在我们的瘢痕诊所接受了病灶内注射5-FU治疗。