Apikian Martine, Goodman Greg
Specialist Cosmetic Laser Clinic, 8th Floor, Trak Centre, 445 Toorak Road, Toorak 5142, Melbourne, Victoria, Australia.
Australas J Dermatol. 2004 May;45(2):140-3. doi: 10.1111/j.1440-0960.2004.00072.x.
Two patients with keloid scars are described. The first patient presented with extensive keloid scarring on both cheeks secondary to acne. The second patient developed a keloid scar on her chest following excision of a mole. Both patients' scars were diagnosed clinically and treated with fortnightly injections of a mixture of 5-fluorouracil and betamethasone acetate and betamethasone sodium phosphate. At each injection session up to 1.6 mL of 5-fluorouracil at a concentration of 500 mg/10 mL and 0.4 mL of betamethasone acetate and betamethasone sodium phosphate (as betamethasone acetate 3 mg in suspension and betamethasone sodium phosphate 3.9 mg in solution) were used. Multiple treatments were required to obtain resolution of the keloid scars. Improvement was maintained in both patients at 1 year post treatment.
本文描述了两名患有瘢痕疙瘩的患者。第一名患者因痤疮导致双侧脸颊出现广泛的瘢痕疙瘩。第二名患者在切除一颗痣后胸部出现了瘢痕疙瘩。两名患者的瘢痕均经临床诊断，并接受了每两周一次的5-氟尿嘧啶与醋酸倍他米松和倍他米松磷酸钠混合物的注射治疗。每次注射时，使用浓度为500mg/10mL的5-氟尿嘧啶最多1.6mL，以及0.4mL的醋酸倍他米松和倍他米松磷酸钠（醋酸倍他米松3mg混悬液和倍他米松磷酸钠3.9mg溶液）。需要多次治疗才能使瘢痕疙瘩消退。两名患者在治疗后1年瘢痕疙瘩均持续改善。
