Harley H R
Thorax. 1976 Jun;31(3):254-64. doi: 10.1136/thx.31.3.254.
A study from Wales of 132 women with cancer of the lung admitted consecutively during the five years 1964-68, and of 13 other women submitted to surgery at an earlier period, showed that the prognosis for women was worse than for men. Every woman except one was followed up for more than five years. Of the 132 women in the consecutive series only five survived for five years, while the five-year survival rate after resection in 35 women was less than one-half of that of men. The cause of the worse prognosis for women in Wales appears to be due to some sex-linked factor. It cannot be explained by the age of the patient or by the histology, location, early or resectability of the growth. The prognosis of cancer of the lung in English, French, and American women is considered. The relative incidence of the disease in women and men is discussed. Sex and nationality appear to be of importance, but the influence of tobacco and other atmospheric carcinogens is obscure.
威尔士一项针对1964年至1968年这五年间连续收治的132名肺癌女性患者，以及13名早期接受手术的其他女性患者的研究表明，女性患者的预后比男性更差。除一名女性外，其他所有女性均接受了超过五年的随访。在连续收治的132名女性患者中，只有5人存活了五年，而35名女性患者切除术后的五年生存率不到男性的一半。威尔士女性预后较差的原因似乎是由于某些与性别相关的因素。这无法用患者的年龄、肿瘤组织学类型、位置、是否早期发现或是否可切除来解释。文中还考虑了英国、法国和美国女性肺癌患者的预后情况，并讨论了该疾病在女性和男性中的相对发病率。性别和国籍似乎很重要，但烟草和其他大气致癌物的影响尚不明确。
