Nakauchi Yoshifumi, Taniguchi Mitsugu, Miyamura Yukiko, Ishise Takuo, Miyazaki Shunichi
Division of Cardiology, Department of Internal Medicine, Kinki University School of Medicine, Osakasayama, Osaka, Japan.
J Cardiol. 2007 Dec;50(6):383-7.
An 18-year-old man was diagnosed with ventricular septal defect after birth. He was asymptomatic until February 2006. He came to our hospital with remittent fever persisting for 2 months. Chest computed tomography showed multiple infiltrative shadows and alpha-streptococcus was detected on blood cultures. Transesophageal echocardiography detected vegetation (1.3 cm) on the right ventricle wall at the point of impact of the shunted bloodstream. We diagnosed pulmonary septic embolism and began to administer penicillin G and gentamicin. Sixteen days later, a new pulmonary septic embolism appeared, so antibiotic treatment was continued at a higher dose. Two weeks later, the vegetation and infiltrative shadow disappeared. Echocardiography showed the ratio of pulmonary to systemic blood flow was 1.2. These findings indicate that patch closure of ventricular septal defect may be necessary for prevention of recurrence of right side infectious endocarditis.
一名18岁男性出生后被诊断为室间隔缺损。2006年2月前他一直无症状。他因持续2个月的弛张热前来我院就诊。胸部计算机断层扫描显示多个浸润性阴影,血培养检测到α溶血性链球菌。经食管超声心动图在分流血流冲击点的右心室壁上检测到赘生物(1.3厘米)。我们诊断为肺脓毒性栓塞,并开始给予青霉素G和庆大霉素治疗。16天后,出现了新的肺脓毒性栓塞,因此以更高剂量继续抗生素治疗。两周后,赘生物和浸润性阴影消失。超声心动图显示肺循环与体循环血流量之比为1.2。这些结果表明,室间隔缺损修补术对于预防右侧感染性心内膜炎复发可能是必要的。