de Medeiros Luciana M, Fransway Anthony F, Taylor James S, Wyman Marcia, Janes Jodith, Fowler Joseph F, Rietschel Robert L
Section of Industrial Dermatology, Department of Dermatology (A-61), Cleveland Clinic, Cleveland, OH 44195, USA.
Contact Dermatitis. 2008 Feb;58(2):97-100. doi: 10.1111/j.1600-0536.2007.01272.x.
Systemic contact dermatitis from nickel has been reported from a number of sources including medical devices and following experimental oral exposure.
To identify other potential sources of systemic nickel exposure.
The internet and published medical literature were searched for complementary and alternative remedies which contain nickel.
We identified and evaluated sources of nickel exposure in 4 homeopathic preparations, which are advertised to treat common skin diseases, as well as in a number of other homeopathic remedies, several herbal products and multivitamin mineral complexes.
Complementary and alternative remedies are an additional source of systemic nickel exposure and at highest doses the potential risk for systemic contact dermatitis in nickel allergic patients should be considered.
包括医疗设备及实验性口服暴露在内,已有多个来源报道了镍所致的系统性接触性皮炎。
确定系统性镍暴露的其他潜在来源。
检索互联网及已发表的医学文献,查找含镍的补充和替代疗法。
我们识别并评估了4种宣称可治疗常见皮肤病的顺势疗法制剂、多种其他顺势疗法药物、几种草药产品及多种维生素矿物质复合物中的镍暴露来源。
补充和替代疗法是系统性镍暴露的额外来源,对于镍过敏患者,应考虑高剂量时发生系统性接触性皮炎的潜在风险。