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权衡与益处:增强绵羊对胃肠道寄生虫的强免疫力的影响

Trade-offs and benefits: implications of promoting a strong immunity to gastrointestinal parasites in sheep.

作者信息

Greer A W

机构信息

Parasitology Division, Moredun Research Institute, Pentlands Science Park, Bush Loan, Scotland, UK.

出版信息

Parasite Immunol. 2008 Feb;30(2):123-32. doi: 10.1111/j.1365-3024.2008.00998.x.

DOI:10.1111/j.1365-3024.2008.00998.x
PMID:18186772
Abstract

The search for sustainable control regimes for gastrointestinal nematode parasites in grazing livestock has resulted in strategies that include assisting sheep to promote a strong immune response. However, the immune response imposes a substantial nutritional cost to the animal which, when nutrient supply is limited, is likely to result in the diversion of nutrients away from productive function to immunological tissues. Therefore, this review examines the potential trade-offs between immune function and productivity that may arise in young grazing sheep. It is hoped that future manipulations intended to promote a strong immunity to gastrointestinal parasites in sheep may be able to minimize these trade-offs to ensure that the productivity of the host is not compromised.

摘要

寻找食草家畜胃肠道线虫寄生虫的可持续控制方法已产生了多种策略,其中包括帮助绵羊增强免疫反应。然而,免疫反应会给动物带来巨大的营养成本,在营养供应有限时,这可能导致营养物质从生产功能转向免疫组织。因此,本综述探讨了幼龄食草绵羊免疫功能与生产力之间可能出现的潜在权衡。希望未来旨在增强绵羊对胃肠道寄生虫免疫力的操作能够尽量减少这些权衡,以确保宿主的生产力不受影响。

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