Wang D L
Department of Respiratory Disease, New Bridge Hospital, Third Military Medical College.
Zhonghua Jie He He Hu Xi Za Zhi. 1991 Dec;14(6):362-3, 378.
Diaphragmatic fatigue (DF) in respiratory distress syndrome (RDS) induced by injection of fat were studied in 7 dogs. After injection of fat, all dogs developed respiratory distress and tachypnea, PaO2 fell to the level lower than 8 kPa. Transdiaphragmatic pressure (Pdi) decreased progressively (P less than 0.05-0.001), Pdi-stimulation frequency (Pdi-F) curve shifted to the right, central frequency (Fc), median frequency (Fm) and high/low frequency ratio (H/L) significantly decreased (P less than 0.05-0.001). It is concluded that the contractile force of the diaphragm progressively decreased after RDS was induced, which suggested the occurrence of DF.
对7只犬进行研究，观察注射脂肪诱导的呼吸窘迫综合征（RDS）中的膈肌疲劳（DF）情况。注射脂肪后，所有犬均出现呼吸窘迫和呼吸急促，动脉血氧分压（PaO2）降至8kPa以下。跨膈压（Pdi）逐渐降低（P<0.05 - 0.001），Pdi-刺激频率（Pdi-F）曲线右移，中心频率（Fc）、中位频率（Fm）和高/低频比（H/L）显著降低（P<0.05 - 0.001）。结论为，诱导RDS后膈肌收缩力逐渐下降，提示发生了DF。
