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增生性玻璃体视网膜病变硅油取出术后视网膜再脱离:一项预后因素分析

Retinal redetachment after silicone oil removal in proliferative vitreoretinopathy: a prognostic factor analysis.

作者信息

Lam Robert F, Cheung Benson T O, Yuen Can Y F, Wong David, Lam Dennis S C, Lai Wico W

机构信息

Hong Kong Eye Hospital, and the Eye Institute, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.

出版信息

Am J Ophthalmol. 2008 Mar;145(3):527-533. doi: 10.1016/j.ajo.2007.10.015. Epub 2008 Jan 11.

Abstract

PURPOSE

To determine the prognostic factors associated with retinal redetachment after 1300-centistokes silicone oil removal in rhegmatogenous retinal detachments (RDs) associated with grade C proliferative vitreoretinopathy (PVR).

DESIGN

Nonrandomized, retrospective, comparative interventional trial.

METHODS

One hundred and forty-seven eyes with RD and grade C PVR treated with silicone oil tamponade, with subsequent silicone oil removal, in an institutional setting. Main outcome measures included anatomic success, defined as complete retinal attachment after silicone oil removal, and best-corrected visual acuity (BCVA) after silicone oil removal.

RESULTS

Silicone oil was removed after a mean tamponade period of 12.4+/-9.8 months. The mean follow-up after silicone oil removal was 22.1+/-18.7 months (range, 6.0 to 71.0 months). The retina remained attached in 120 eyes after oil removal. The overall anatomic success rate was 81.6%+/-3.2%. Logistic regression showed that an increased number of previous unsuccessful RD surgeries (odds ratio [OR], 0.39; 95% confidence interval [CI], 0.19 to 0.80; P=.010) and longer axial lengths (OR, 0.42; 95% CI, 0.15 to 0.87; P=.032) were associated with a lower anatomic success rate. Previous vitrectomy, previous scleral buckling procedure, 12% perfluoropropane-air exchange immediately after silicone oil removal, and duration of silicone oil tamponade were not statistically associated with the anatomic success rate. Anatomic success was associated with a significantly better BCVA (1.169+/-0.475 vs 1.520+/-0.381 logarithm of the minimum angle of resolution; P<.001).

CONCLUSIONS

The number of previous surgeries and axial length, rather than the nature of the previous surgical procedures, were significant prognostic factors for anatomic success after silicone oil removal.

摘要

目的

确定在与C级增生性玻璃体视网膜病变(PVR)相关的孔源性视网膜脱离(RD)患者中,1300厘沲硅油取出术后视网膜再脱离的相关预后因素。

设计

非随机、回顾性、对比性干预试验。

方法

147例患有RD和C级PVR的患者在机构环境中接受硅油填塞治疗,随后取出硅油。主要观察指标包括解剖学成功,定义为取出硅油后视网膜完全附着,以及取出硅油后的最佳矫正视力(BCVA)。

结果

硅油填塞平均时间为12.4±9.8个月后取出硅油。取出硅油后的平均随访时间为22.1±18.7个月(范围6.0至71.0个月)。取出硅油后120只眼的视网膜保持附着。总体解剖学成功率为81.6%±3.2%。逻辑回归显示,既往RD手术失败次数增加(比值比[OR],0.39;95%置信区间[CI],0.19至0.80;P = 0.010)和眼轴长度较长(OR,0.42;95%CI,0.15至0.87;P = 0.032)与较低的解剖学成功率相关。既往玻璃体切除术、既往巩膜扣带术、取出硅油后立即进行12%全氟丙烷-空气交换以及硅油填塞持续时间与解剖学成功率无统计学关联。解剖学成功与显著更好的BCVA相关(最小分辨角对数:1.169±0.475 vs 1.520±0.381;P<0.001)。

结论

既往手术次数和眼轴长度,而非既往手术方式的性质,是硅油取出术后解剖学成功的重要预后因素。

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