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增殖性玻璃体视网膜病变的防治:在高危病例中,将硅油作为计划性两阶段手术用于原发性视网膜脱离手术。

Prevention and control of proliferative vitreoretinopathy: primary retinal detachment surgery using silicone oil as a planned two-stage procedure in high-risk cases.

作者信息

Alexander P, Prasad R, Ang A, Poulson A V, Scott J D, Snead M P

机构信息

Vitreoretinal Service, Addenbrooke's Hospital, Cambridge, UK.

出版信息

Eye (Lond). 2008 Jun;22(6):815-8. doi: 10.1038/sj.eye.6702719. Epub 2007 Feb 2.

Abstract

AIMS

For rhegmatogenous retinal detachment, reattachment with a single procedure is associated with better visual outcomes. In the past, silicone oil has been used mostly as a last resort following failed primary surgery. This study evaluates a novel approach to patients at high risk of primary failure, using silicone tamponade as the primary stage of a planned two-stage procedure.

METHODS

We report a series of 140 eyes that underwent primary surgery for rhegmatogenous retinal detachment. Patients at higher risk of surgical failure (eg giant retinal tear, inability to posture, poor view, uncertainty of location of primary break, primary proliferative vitreoretinopathy (PVR), multiple tears with rolled posterior edges, retinoschisis/detachment, staphyloma with macular hole) were managed by a planned staged procedure using primary silicone oil tamponade. This was followed by silicone removal at a later date.

RESULTS

Fifty-four eyes underwent scleral buckling alone, with primary success in 52/54 (96%). Fifty-three eyes underwent vitrectomy and gas, achieving primary success in 50/53 (94%). Thirty-three eyes were classified high risk and managed with primary silicone. Silicone was safely removed in 22/25. In eight eyes, silicone was retained without attempt at removal. In total, primary retinal reattachment was achieved in 128 of 140 eyes (91.4%). Of these, 124 (97%) did not require long-term tamponade. Only four eyes (2.9%) developed PVR.

DISCUSSION

A planned two-stage approach to highrisk cases of retinal detachment using primary silicone oil tamponade followed by silicone removal can achieve a high primary reattachment rate with less than 3% incidence of PVR.

摘要

目的

对于孔源性视网膜脱离,单次手术复位与更好的视觉效果相关。过去,硅油大多在初次手术失败后作为最后的手段使用。本研究评估一种针对初次手术失败高风险患者的新方法,将硅油填塞作为计划中的两阶段手术的第一阶段。

方法

我们报告了一系列140只接受孔源性视网膜脱离初次手术的眼睛。手术失败风险较高的患者(例如巨大视网膜裂孔、无法保持体位、视野不佳、原发裂孔位置不确定、原发性增生性玻璃体视网膜病变(PVR)、多个后缘卷曲的裂孔、视网膜劈裂/脱离、伴有黄斑裂孔的葡萄肿)采用计划的分期手术,首先进行硅油填塞,随后在晚些时候取出硅油。

结果

54只眼睛仅接受巩膜扣带术,52/54(96%)获得初次成功。53只眼睛接受玻璃体切除术和气体填充,50/53(94%)获得初次成功。33只眼睛被归类为高风险并采用初次硅油治疗。22/25的硅油被安全取出。8只眼睛保留了硅油,未尝试取出。总共140只眼睛中有128只(91.4%)实现了视网膜初次复位。其中,124只(97%)不需要长期填塞。只有4只眼睛(2.9%)发生了PVR。

讨论

对于视网膜脱离高风险病例,采用初次硅油填塞随后取出硅油的计划两阶段方法可以实现高初次复位率,PVR发生率低于3%。

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