Quiram Polly A, Gonzales Christine R, Hu Wanda, Gupta Anurag, Yoshizumi Marc O, Kreiger Allan E, Schwartz Steven D
Jules Stein Eye Institute, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA.
Ophthalmology. 2006 Nov;113(11):2041-7. doi: 10.1016/j.ophtha.2006.05.039. Epub 2006 Sep 6.
To report the anatomic and functional outcomes of patients treated with vitrectomy and inferior retinectomy for recurrent, rhegmatogenous retinal detachment complicated by proliferative vitreoretinopathy (PVR).
Retrospective, noncomparative, interventional case series.
Fifty-six patients with recurrent, rhegmatogenous retinal detachments complicated by PVR who underwent an inferior retinectomy for repair.
Retrospective review over a 6-year period of patients treated with vitrectomy and inferior retinectomy.
The primary outcome was anatomic success, defined as complete retinal reattachment. Secondary outcomes included change in visual acuity, the mean number of operations required for complete retinal reattachment, number of operations before retinectomy, use of silicone oil tamponade, location and extent of retinectomy, whether lensectomy was undertaken, and incidence of postoperative complications.
Complete retinal reattachment was achieved in 52 of 56 patients (93%), with a mean follow-up of 25 months (range, 6-70 months). After retinal reattachment, visual acuity was improved or stabilized in 39 of 56 patients (70%). The mean number of operations for retinal detachment before diagnosis of PVR requiring retinectomy was 1.8 (range, 1-5). Patients undergoing radical anterior vitreous base dissection and lensectomy at the time of first retinectomy had a higher success rate than those who did not: 74% versus 38%, respectively (P = 0.011). Furthermore, tamponade with silicone oil had a higher success rate than tamponade with gas: 71% versus 18%, respectively (P = 0.002). Of the 56 patients, 9 (16%) had 1 or more of the following complications: keratopathy requiring penetrating keratoplasty (n = 4), glaucoma requiring aqueous shunt device (n = 3), and hypotony (n = 3). Silicone oil removal was performed in 26 of 45 patients (58%) before the last follow-up visit, with a 1 in 26 (4%) redetachment rate.
When combined with anterior base dissection, inferior retinectomy may be useful in the surgical treatment of complex PVR-related retinal detachment. The authors show that with lensectomy, radical anterior base dissection, and inferior retinectomy, anatomic success rates are improved and visual function can be maintained. In addition, silicone oil offers an advantage over gas tamponade in these cases.
报告接受玻璃体切除术和视网膜下切除术治疗复发性孔源性视网膜脱离并伴有增生性玻璃体视网膜病变(PVR)患者的解剖和功能结果。
回顾性、非对照、干预性病例系列研究。
56例复发性孔源性视网膜脱离并伴有PVR且接受视网膜下切除术修复的患者。
对接受玻璃体切除术和视网膜下切除术治疗的患者进行为期6年的回顾性研究。
主要观察指标为解剖学成功,定义为视网膜完全复位。次要观察指标包括视力变化、视网膜完全复位所需的平均手术次数、视网膜下切除术前的手术次数、硅油填充的使用情况、视网膜下切除的位置和范围、是否进行晶状体切除术以及术后并发症的发生率。
56例患者中有52例(93%)实现了视网膜完全复位,平均随访时间为25个月(范围6 - 70个月)。视网膜复位后,56例患者中有39例(70%)视力得到改善或稳定。在诊断为PVR需要进行视网膜下切除术之前,视网膜脱离的平均手术次数为1.8次(范围1 - 5次)。首次视网膜下切除术时进行彻底的前部玻璃体基底部剥离和晶状体切除术的患者成功率高于未进行者:分别为74%和38%(P = 0.011)。此外,硅油填充的成功率高于气体填充:分别为71%和18%(P = 0.002)。56例患者中有9例(16%)出现以下1种或多种并发症:需要穿透性角膜移植术的角膜病变(n = 4)、需要房水引流装置的青光眼(n = 3)和低眼压(n = 3)。在最后一次随访前,45例患者中有26例(58%)进行了硅油取出术,视网膜再脱离率为1/26(4%)。
与前部基底部剥离联合应用时,视网膜下切除术可能有助于治疗复杂的PVR相关视网膜脱离。作者表明,通过晶状体切除术、彻底的前部基底部剥离和视网膜下切除术,解剖学成功率得以提高,视觉功能得以维持。此外,在这些病例中,硅油填充优于气体填充。