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[周围性面神经麻痹的预后评估,特别参考神经电图检查(作者译)]

[Prognostic assessment in peripheral facial nerve paralysis with particular reference to electroneurography (author's transl)].

作者信息

Mamoli B

出版信息

Wien Klin Wochenschr Suppl. 1976;53:3-28.

PMID:181919
Abstract

Electrophysiological investigations were carried out on 20 healthy controls and 130 patients with peripheral facial nerve paralysis. The aetiology was as follows: idiopathic (Bell's palsy) in 60 cases, viral in 29, traumatic in 18, postoperative in 4, in connexion with chronic otitis media in 6, diabetes mellitus in 4, positive rheumatological tests in 3, disturbed lipid metabolism in 2, the Melkersson-Rosenthal syndrome in 1, as a complication of pregnancy in 2, and in association with a tumour in 1 case. The compound action potential (CAP) of the orbicularis oris muscle was determinedi n 370 occasions in a right/left comparision, the record of the muscle response was intergrated over the time of action (IAR) on 32 occasions and trison of 255 occasions. The normal values are given in the first place and their dependence of the age of the subject. Then, the prognostic sifnficance of the above-mentioned parameters is investigated in cases of peripheral facial nerve paralysis. It is apparent that the determination of the CAP in a right/left comparison is a valuable prognostic guide as early as the 4th day, insofar as a decrease in this parameter of under 50% can be interpreted as a favourable sign and satisfactory reversal of the paralysis can be expected within 6-8 weeks. By contrast, a decrease of over 70% in the CAP is a bad prognostic sign, indicative of presumably only a poor trend to reversal of the paralysis. An intermediate depression of the CAP in the range of 50-70% signifies an expected moderate recovery within 6-8 weeks ahe case of CAP determination at the time of maximum amplitude depression (as opposed to the 4th day), then a decrease of less than 70% is taken to be indicative of satisfactory functional recovery within 6-8 weeks; a decrease of 95-100% signifies a bad prognosis, whilst a decrease amounting to between 70 and 95% carries an uncertain prognosis. The maximum decrease in amplitude was registered on the 8th day on average; the range lay between the 4th and the 14th day. An exception to these figures was the delayed response of the CAP in the case of 6 patients, 5 of whom showed a maximum decrease during the 3rd week and the last patient as late as the 4th week following the onset of facial nerve paresis. Similar reliance can be placed on the prognostic value of the IAR. however, the decrease in the IAR is smaller than that of the CAP measured on the same potential in a right/left comparison, so that a decrease in the IAR of over 60% can already herald a poor recovery. Repeated determination of the latency in cases of facial nerve paralysis showed that the mean latency value for the entire group of patients was slightly prolonged at the end of the 1st week, but the latency values obtained in any one particular patient are of no prognostic significance. A comparison between CAP and latency values obtained with the opposite (i.e...

摘要

对20名健康对照者和130例周围性面神经麻痹患者进行了电生理检查。病因如下:特发性(贝尔麻痹)60例,病毒性29例,创伤性18例,术后4例,与慢性中耳炎有关6例,糖尿病4例,风湿检查阳性3例,脂质代谢紊乱2例,梅尔克森 - 罗森塔尔综合征1例,妊娠并发症2例,与肿瘤有关1例。在370次右/左对比中测定了口轮匝肌的复合动作电位(CAP),在32次中记录了肌肉反应在动作时间内的积分(IAR),并进行了255次对比。首先给出正常值及其与受试者年龄的关系。然后,研究上述参数在周围性面神经麻痹病例中的预后意义。很明显,早在第4天,右/左对比测定CAP就是一个有价值的预后指标,因为该参数下降50%以下可解释为有利迹象,预计在6 - 8周内麻痹会令人满意地恢复。相比之下,CAP下降超过70%是不良预后指标,表明麻痹恢复趋势可能很差。CAP下降在50 - 70%之间表示预计在6 - 8周内中度恢复。如果在最大振幅下降时(与第4天相反)测定CAP,那么下降小于70%表示在6 - 8周内功能恢复良好;下降95 - 100%表示预后不良,而下降在70%至95%之间预后不确定。平均在第8天记录到振幅最大下降;范围在第4天至第14天之间。有6例患者的CAP反应延迟是这些数字的一个例外,其中5例在面神经麻痹发作后的第3周出现最大下降,最后1例直到第4周才出现。IAR的预后价值也有类似的可靠性。然而,IAR的下降幅度小于右/左对比中在相同电位下测定的CAP下降幅度,因此IAR下降超过60%可能已经预示恢复不佳。面神经麻痹病例中潜伏期的重复测定表明,在第1周结束时,整个患者组的平均潜伏期值略有延长,但任何一名特定患者获得的潜伏期值没有预后意义。比较CAP和用对侧(即……)获得的潜伏期值

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