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气功练习对原发性高血压的临床疗效:随机对照试验的荟萃分析。

Clinical effect of qigong practice on essential hypertension: a meta-analysis of randomized controlled trials.

作者信息

Guo Xinfeng, Zhou Bin, Nishimura Tsutomu, Teramukai Satoshi, Fukushima Masanori

机构信息

National DME Training Center, Guangzhou University of Traditional Chinese Medicine, Guangzhou, People's Republic of China.

出版信息

J Altern Complement Med. 2008 Jan-Feb;14(1):27-37. doi: 10.1089/acm.2007.7213.

DOI:10.1089/acm.2007.7213
PMID:18199012
Abstract

OBJECTIVES

This study was designed to quantitatively assess the effectiveness of self-practiced qigong for treatment of essential hypertension.

METHODS

Six major electronic databases were searched up to July 2006 to retrieve any potential randomized controlled trials designed to evaluate the clinical effectiveness of self-practiced qigong for essential hypertension reported in any language, with main outcome measures as systolic blood pressure (SBP) and diastolic blood pressure (DBP). The quality of included studies were assessed with the Jadad Scale and a customized standard quality assessment scale.

RESULTS

Ninety-two (92) studies were identified. Nine (9) of these studies qualified for meta-analysis, comprising a total of 908 cases. Results were as follows: (1) The mean decrease of SBP in those practicing qigong was a 17.03 mm Hg reduction (95% confidence interval (CI) 11.53-22.52) compared with nonspecific intervention controls, but not superior to that in drug controls (1.19 mm Hg, 95% CI -5.40-7.79) and conventional exercise controls (-1.51 mm Hg, 95% CI -6.98-3.95). (2) Mean decrease of DBP in those practicing qigong was 9.98 mm Hg (95% CI 2.55-17.41) compared with nonspecific intervention controls, but not superior to that in drug controls (2.49 mm Hg, 95% CI -0.16-5.13) and conventional exercise controls (-1.59 mm Hg, 95% CI -4.91-1.74). (3) No obvious side effects were identified.

CONCLUSIONS

Self-practiced qigong for less than 1 year is better in decreasing BP in patients with essential hypertension than in no-treatment controls, but is not superior to that in active controls. More methodologically strict studies are needed to prove real clinical benefits of qigong, and to explore its potential mechanism.

摘要

目的

本研究旨在定量评估自我练习气功治疗原发性高血压的有效性。

方法

检索截至2006年7月的六个主要电子数据库,以检索任何语言报道的、旨在评估自我练习气功治疗原发性高血压临床有效性的潜在随机对照试验,主要结局指标为收缩压(SBP)和舒张压(DBP)。采用Jadad量表和定制的标准质量评估量表对纳入研究的质量进行评估。

结果

共识别出92项研究。其中9项研究符合荟萃分析标准,共908例病例。结果如下:(1)与非特异性干预对照组相比,练习气功者的SBP平均降低17.03 mmHg(95%置信区间(CI)11.53 - 22.52),但不优于药物对照组(1.19 mmHg,95% CI -5.40 - 7.79)和传统运动对照组(-1.51 mmHg,95% CI -6.98 - 3.95)。(2)与非特异性干预对照组相比,练习气功者的DBP平均降低9.98 mmHg(95% CI 2.55 - 17.41),但不优于药物对照组(2.49 mmHg,95% CI -0.16 - 5.13)和传统运动对照组(-1.59 mmHg,95% CI -4.91 - 1.74)。(3)未发现明显副作用。

结论

自我练习气功不到1年对原发性高血压患者降低血压的效果优于无治疗对照组,但不优于积极对照组。需要更多方法学严格的研究来证明气功的实际临床益处,并探索其潜在机制。

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