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气功对收缩压和舒张压降低的影响:系统评价与荟萃分析和试验序贯分析。

Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis.

机构信息

Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.

Malaysian Research Institute on Ageing, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.

出版信息

BMC Complement Med Ther. 2021 Jan 6;21(1):8. doi: 10.1186/s12906-020-03172-3.

Abstract

BACKGROUND

The benefits of qigong for systolic and diastolic blood pressure (BP) reduction have been noted in previously published systematic reviews; however, the data on its effectiveness has been at best scarce. We aimed to update the evidence of qigong on blood pressure reduction after taking into consideration the risks of random error and reliability of data in the cumulative meta-analysis using trial sequential analysis (TSA).

METHODS

Included trials were assessed using Cochrane risk of bias instrument. We performed meta-analysis with random-effects model and random errors were evaluated with TSA. We performed the search for the eligible randomized controlled trial (RCT) through Medline, Cinahl, Cochrane Central Register of Controlled Trials and also PubMed.

RESULTS

A total of 370 subjects sourced from seven eligible RCTs were entered into the analysis. The pooled results demonstrated the significant reduction with the use of qigong of the systolic blood pressure [weighted mean difference (WMD), - 10.66 mmHg (95% confidence interval (CI) = - 17.69,-3.62, p < 0.001] and diastolic BP [WMD, - 6.76 mmHg, 95% CI = - 12.22, - 1.30, p < 0.001] as compared to the control group.

CONCLUSIONS

Significant reductions in BP is seen with the use of qigong as compared with the control group, suggesting that qigong may be used as a complementary therapy in the somewhat complicated management of hypertension.

摘要

背景

气功对收缩压和舒张压(BP)降低的益处已在先前发表的系统评价中得到证实;然而,关于其有效性的数据最多是稀缺的。我们旨在通过累积荟萃分析中的试验序贯分析(TSA)考虑随机误差和数据可靠性的风险,更新气功对降低血压的证据。

方法

使用 Cochrane 偏倚风险工具评估纳入试验。我们使用随机效应模型进行荟萃分析,并使用 TSA 评估随机误差。我们通过 Medline、Cinahl、Cochrane 对照试验中心注册库和 PubMed 搜索合格的随机对照试验(RCT)。

结果

共有 370 名来自 7 项合格 RCT 的受试者纳入分析。汇总结果表明,与对照组相比,气功的使用显著降低了收缩压[加权均数差(WMD),-10.66mmHg(95%置信区间(CI)= -17.69,-3.62,p<0.001)]和舒张压[WMD,-6.76mmHg,95%CI=-12.22,-1.30,p<0.001]。

结论

与对照组相比,气功的使用使 BP 显著降低,这表明气功可能在高血压的复杂管理中用作补充治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36ee/7789757/12d1d3ed026e/12906_2020_3172_Fig1_HTML.jpg

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