Vilar Fernando Crivelenti, Castro Gleusa de, Moya Maria Janete, Martinelli Ana de Lourdes Candolo, De Santis Gil Cunha, Cozac Ana Paula Costa Nunes da Cunha, Figueiredo José Fernando de Castro
Division of Infectious and Tropical Diseases, Department of Internal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP.
Rev Soc Bras Med Trop. 2007 Nov-Dec;40(6):678-80. doi: 10.1590/s0037-86822007000600016.
Two cases of autoimmune hemolytic anemia that occurred during the treatment of chronic hepatitis C with pegylated alpha-2a interferon and ribavirin, in HIV coinfected patients, are presented and described. The late occurrence (after six months of therapy) of this severe hemolytic anemia leads to the recommendation that hemoglobin levels should be monitored throughout the treatment period, even among patients who presented stable hemoglobin levels in the preceding months.
