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[在伯南布哥州乌纳河畔圣本托腹泻流行后地区循环杀弧菌抗体的重要性]

[The importance of circulating vibriocidal antibodies in a pos-epidemic region of diarrhea, São Bento do Una, State of Pernambuco].

作者信息

Filizola Lúcia Roberta de Souza, Figueirôa Angela Cristina Torres de Araújo, Araújo Maria Cristina D de, Cavalcanti Valdelúcia de Oliveira, Lima Cristiani Maria de, Hofer Ernesto

机构信息

Laboratório Central de Saúde Pública Dr. Milton Bezerra Sobral, Recife, PE.

出版信息

Rev Soc Bras Med Trop. 2007 Nov-Dec;40(6):686-9. doi: 10.1590/s0037-86822007000600018.

Abstract

The levels of vibriocidal antibodies were investigated among 41 adults without any past or present history of diarrhea due to Vibrio cholerae O1 who were living in the municipality of São Bento do Una, Pernambuco. A diarrhea outbreak occurred in this locality at the beginning of 2004, involving multiple bacterial agents, including Vibrio cholerae. The microtitration test was used to investigate the presence of anti-Ogawa and anti-Inaba vibriocidal serum antibodies. Vibriocidal titers e" 1:640 were considered indicative of infection by Vibrio cholerae O1. The frequency of the reagents was 36 (87.8%) for the Ogawa serovar, which showed that Vibrio cholerae O1 was possibly circulating during and/or after the diarrhea epidemic.

摘要

对居住在伯南布哥州圣本托杜乌纳市、41名既往及目前均无霍乱弧菌O1所致腹泻病史的成年人,检测其杀弧菌抗体水平。2004年初,该地区发生腹泻暴发,涉及多种细菌病原体,包括霍乱弧菌。采用微量滴定试验检测抗小川型和抗稻叶型杀弧菌血清抗体的存在情况。杀弧菌效价≥1:640被视为感染霍乱弧菌O1的指征。小川血清型的反应率为36例(87.8%),这表明霍乱弧菌O1可能在腹泻流行期间和/或之后传播。

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