Sutherland D E, Gruessner A, Moudry-Munns K
Department of Surgery, University of Minnesota, Minneapolis.
Clin Transpl. 1991:31-8.
More than 3,600 pancreas transplants were reported to the International Pancreas Transplant Registry by the end of 1991. More than 2,200 of the transplants were performed in the United States, including more than 1,600 that had been reported to the UNOS Registry since October 1, 1987. Of these, more than 1,400 have been entered into a computerized data base, and in more than 1,300 there was sufficient information for actuarial patient survival and graft functional (insulin-independent) survival rates to be calculated. Overall patient (n = 1,362) survival and pancreas graft (n = 1,340) functional survival rates were 91% and 72%, respectively at 1 year; the patient and graft survival rates were 86% and 65%, respectively, at 2 years; and 80% and 57%, respectively, at 3 years posttransplant. In the 3 major recipient categories, simultaneous pancreas/kidney (SPK) transplants (n = 1,149), pancreas after kidney (PAK) transplants (n = 131), and pancreas transplants alone (PTA) cases (n = 82), the 1-year patient survival rates were 90%, 92%, and 92%, with the corresponding survival rates at 2 years being 87%, 89%, and 89%, and at 3 years being 80%, 83%, and 83% (p = NS). The corresponding pancreas graft functional survival rates at 1 year in the 3 recipient categories were 76% for SPK (n = 1,131), 54% for PAK (n = 127), and 47% for PTA (n = 82).(ABSTRACT TRUNCATED AT 250 WORDS)
截至1991年底，国际胰腺移植登记处共收到3600多例胰腺移植报告。其中2200多例在美国进行，包括自1987年10月1日起向器官共享联合网络（UNOS）登记处报告的1600多例。在这些病例中，1400多例已录入计算机数据库，1300多例有足够信息用于计算患者精算生存率和移植物功能（不依赖胰岛素）生存率。总体患者（n = 1362）1年生存率和胰腺移植物（n = 1340）功能生存率分别为91%和72%；移植后2年患者和移植物生存率分别为86%和65%；3年时分别为80%和57%。在3个主要受者类别中，胰肾联合移植（SPK，n = 1149）、肾移植后胰腺移植（PAK，n = 131）和单纯胰腺移植（PTA，n = 82），1年患者生存率分别为90%、92%和92%，2年相应生存率分别为87%、89%和89%，3年时分别为80%、83%和83%（p =无显著性差异）。3个受者类别中，1年时相应的胰腺移植物功能生存率，SPK为76%（n = 1131），PAK为54%（n = 127），PTA为47%（n = 82）。（摘要截取自250词）
