Figueroa Barrios R
Servicio de Gastroenterología, Hospital Nacional Edgardo Rebagliati Martins, IPSS. Lima, Peru.
Rev Gastroenterol Peru. 1991;11(2):119-28.
Hepatic encephalopathy is still today a diagnostic and treatment challenge for any clinician, distinguishing two types: that occurring in patients with acute liver disease and that associated with chronic liver disease. Despite our limited understanding of the pathogenesis of this disorder, treatment for hepatic encephalopathy in patients with chronic liver disease is reasonable satisfactory. Identification and treatment of precipitating factors and lactulose and lactitol therapy, still remain the most important aspects of management. In our country, we have used lactose, a natural disacharide, with the same good results gotten with the synthetic disacharide. Hepatic transplantation has become a realistic therapeutic option in the management of patients with intractable hepatic encephalopathy and is the only effective treatment for hepatic encephalopathy associated with fulminant hepatic failure.
肝性脑病如今仍是每位临床医生面临的诊断和治疗难题,可分为两种类型:急性肝病患者发生的肝性脑病以及与慢性肝病相关的肝性脑病。尽管我们对这种疾病的发病机制了解有限,但慢性肝病患者肝性脑病的治疗效果还算令人满意。识别并治疗诱发因素以及使用乳果糖和乳糖醇进行治疗,仍然是管理的最重要方面。在我国,我们使用了天然二糖乳糖,其效果与合成二糖相同。肝移植已成为治疗顽固性肝性脑病患者的一种切实可行的治疗选择,并且是暴发性肝衰竭相关肝性脑病的唯一有效治疗方法。