Yang Jian, Hu Chengcheng, Hu Han, Yu Rongdong, Xia Zhen, Ye Xiuzi, Zhu Jun
Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029.
Bioinformatics. 2008 Mar 1;24(5):721-3. doi: 10.1093/bioinformatics/btm494. Epub 2008 Jan 17.
QTLNetwork is a software package for mapping and visualizing the genetic architecture underlying complex traits for experimental populations derived from a cross between two inbred lines. It can simultaneously map quantitative trait loci (QTL) with individual effects, epistasis and QTL-environment interaction. Currently, it is able to handle data from F(2), backcross, recombinant inbred lines and double-haploid populations, as well as populations from specific mating designs (immortalized F(2) and BC(n)F(n) populations). The Windows version of QTLNetwork was developed with a graphical user interface. Alternatively, the command-line versions have the facility to be run in other prevalent operating systems, such as Linux, Unix and MacOS.
QTLNetwork是一个软件包，用于对由两个近交系杂交产生的实验群体复杂性状的遗传结构进行定位和可视化。它可以同时定位具有个体效应、上位性和QTL-环境互作的数量性状基因座（QTL）。目前，它能够处理来自F(2)、回交、重组自交系和双单倍体群体的数据，以及来自特定交配设计的群体（永生化F(2)和BC(n)F(n)群体）。QTLNetwork的Windows版本是通过图形用户界面开发的。另外，命令行版本可以在其他流行的操作系统（如Linux、Unix和MacOS）中运行。
