Nansel Tonja R, Gellar Lauren, McGill Adrienne
Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
Diabetes Care. 2008 Apr;31(4):695-7. doi: 10.2337/dc07-1879. Epub 2008 Jan 17.
The purpose of this study was to test the effect of high glycemic index (HGI) and low glycemic index (LGI) meals on blood glucose levels using continuous blood glucose monitoring in youths with type 1 diabetes.
A total of 20 youths on basal-bolus regimens consumed macronutrient-matched HGI and LGI meals 1 day each in a controlled setting in varying order following consumption of a standardized evening meal. Medtronic MiniMed Continuous Glucose Monitoring Systems were used to assess blood glucose (BG) profiles.
Participants demonstrated significantly lower daytime mean BG, BG area >180 mg/dl, and high BG index when consuming LGI meals but no differences for daytime BG area <70 mg/dl, daytime low BG index, or any nighttime values. Significantly more BG values <80 mg/dl were treated on LGI days.
Findings indicate that consumption of an LGI diet may reduce glucose excursions, improving glycemic control.
本研究旨在通过连续血糖监测，测试高血糖指数（HGI）餐和低血糖指数（LGI）餐对1型糖尿病青少年血糖水平的影响。
共有20名采用基础-餐时胰岛素治疗方案的青少年，在食用标准化晚餐后，于受控环境中，以不同顺序分别食用了1天的宏量营养素匹配的HGI餐和LGI餐。使用美敦力MiniMed连续血糖监测系统评估血糖（BG）曲线。
参与者在食用LGI餐时，日间平均BG、BG面积>180 mg/dl和高BG指数显著降低，但日间BG面积<70 mg/dl、日间低BG指数或任何夜间值无差异。在LGI日，显著更多的BG值<80 mg/dl得到了治疗。
研究结果表明，食用LGI饮食可能会减少血糖波动，改善血糖控制。
