Martín-Dávila P, Fortún J, López-Vélez R, Norman F, Montes de Oca M, Zamarrón P, González M I, Moreno A, Pumarola T, Garrido G, Candela A, Moreno S
Servicio de Enfermedades Infecciosas, Hospital Ramón y Cajal, Ctra. Colmenar km. 9,100, 28034 Madrid, Spain.
Clin Microbiol Rev. 2008 Jan;21(1):60-96. doi: 10.1128/CMR.00021-07.
In recent years, the increasing number of donors from different regions of the world is providing a new challenge for the management and selection of suitable donors. This is a worldwide problem in most countries with transplantation programs, especially due to the increase in immigration and international travel. This paper elaborates recommendations regarding the selection criteria for donors from foreign countries who could potentially transmit tropical or geographically restricted infections to solid-organ transplant recipients. For this purpose, an extensive review of the medical literature focusing on viral, fungal, and parasitic infections that could be transmitted during transplantation from donors who have lived or traveled in countries where these infections are endemic has been performed, with special emphasis on tropical and imported infections. The review also includes cases described in the literature as well as risks of transmission during transplantation, microbiological tests available, and recommendations for each infection. A table listing different infectious agents with their geographic distributions and specific recommendations is included.
近年来，来自世界不同地区的捐赠者数量不断增加，这给合适捐赠者的管理和选择带来了新的挑战。在大多数开展移植项目的国家，这都是一个全球性问题，尤其是由于移民和国际旅行的增加。本文阐述了关于外国捐赠者选择标准的建议，这些捐赠者可能会将热带或地理上受限的感染传播给实体器官移植受者。为此，对医学文献进行了广泛回顾，重点关注那些在移植过程中可能由曾在这些感染流行国家生活或旅行过的捐赠者传播的病毒、真菌和寄生虫感染，特别强调热带和输入性感染。该回顾还包括文献中描述的病例、移植过程中的传播风险、可用的微生物检测方法以及针对每种感染的建议。文中包含了一个列出不同感染因子及其地理分布和具体建议的表格。
