Division of Infectious Diseases, Emory University School of Medicine, 550 Peachtree Street, MOT 7th Floor TravelWell, Atlanta, GA 30308, USA.
Int J Infect Dis. 2010 Mar;14(3):e189-96. doi: 10.1016/j.ijid.2009.04.021. Epub 2009 Aug 3.
The number of transplant recipients with tropical infectious diseases is growing due to increasing international travel and the rising number of transplants taking place in the tropics and subtropics. With increases in population migration, the prevalence of individuals infected with geographically restricted organisms also rises. There are three potential categories of tropical infections in transplant patients: (1) donor-related infections transmitted by the graft or through transfusion of blood products; (2) reactivation or recrudescence of latent infections in the donor recipient; and (3) de novo acquisition of infection in the post-transplant period through the traditional route of infection. We present an overall discussion of the association of parasitic (protozoa and helminths) and non-parasitic (viral, bacterial, and fungal) tropical infectious diseases and solid-organ and hematopoietic transplantation. We also suggest potential screening guidelines for some of these tropical infections.
由于国际旅行的增加以及热带和亚热带地区进行的移植手术数量的增加,患有热带传染病的移植受者的数量正在增加。随着人口迁移的增加,感染地理限制生物的个体的流行率也会上升。移植患者中存在三种潜在的热带感染类别:(1)供体相关感染,通过移植物或通过输血的血液制品传播;(2)供体受者中潜伏感染的再激活或复发;和(3)在移植后通过传统感染途径新获得的感染。我们对寄生虫(原生动物和蠕虫)和非寄生虫(病毒、细菌和真菌)热带传染病与实体器官和造血移植的关系进行了全面讨论。我们还为其中一些热带感染提出了潜在的筛查指南。