Pathophysiology of diabetic nephropathy.

Diabetic nephropathy is the primary etiology of chronic kidney disease and kidney failure. With the incidence of type 2 diabetes rapidly increasing in the United States, it is imperative for health care professionals to clearly understand the mechanism of this condition and the implications for prevention. Early recognition of the diabetic state and tight serum glucose control can help prevent the consequence of diabetic nephropathy and its associated life-altering comorbidities.