Abood Gerard, Bowen Matthew, Potkul Ronald, Aranha Gerard, Shoup Margo
Division of Surgical Oncology, Department of Surgery, Loyola University Medical Center, 2160 S. First Ave., Maywood, IL 60153, USA.
Am J Surg. 2008 Mar;195(3):370-3; discussion 373. doi: 10.1016/j.amjsurg.2007.12.012.
The role for liver resection in metastatic ovarian cancer has not been defined. The aim of the current study was to investigate the validity of hepatic resection as a treatment option in metastatic ovarian cancer.
Retrospective review of a single institution's experience of patients undergoing hepatic resection for metastatic ovarian cancer from 1998-2006.
Ten patients underwent resection for metastatic ovarian cancer. Primary tumor type included serous cystadenocarcinoma (n = 8), granulosa cell (n = 1), and yolk sac (n = 1). Median disease-free interval was 48 months. Liver resections included trisegmentectomy (n = 4), lobectomy (n = 4), and bisegmentectomy(n = 1). Additional surgeries included diaphragm resection (n = 60), bowel resection, (n = 30), and adrenalectomy (n = 10). The median overall survival following liver resection was 33 months.
Liver resection for metastatic ovarian cancer is safe and is associated with long-term survival in some patients. Larger analysis may lead to the identification of prognostic factors associated with improved outcomes.
肝切除在转移性卵巢癌中的作用尚未明确。本研究的目的是探讨肝切除作为转移性卵巢癌治疗选择的有效性。
回顾性分析一家机构1998年至2006年期间对转移性卵巢癌患者进行肝切除的经验。
10例患者接受了转移性卵巢癌的肝切除。原发肿瘤类型包括浆液性囊腺癌（n = 8）、颗粒细胞瘤（n = 1）和卵黄囊瘤（n = 1）。无病生存期的中位数为48个月。肝切除包括三段切除术（n = 4）、叶切除术（n = 4）和二段切除术（n = 1）。其他手术包括膈肌切除术（n = 60）、肠切除术（n = 30）和肾上腺切除术（n = 10）。肝切除术后的总生存期中位数为33个月。
转移性卵巢癌的肝切除是安全的，并且在一些患者中与长期生存相关。更大规模的分析可能会确定与改善预后相关的预后因素。
