Wood L R J, Peat G, Thomas E, Duncan R
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, UK.
Osteoarthritis Cartilage. 2008 Jun;16(6):647-53. doi: 10.1016/j.joca.2007.10.007. Epub 2008 Jan 22.
To estimate the contribution of selected non-articular conditions (NACs) to pain severity and functional limitation in community-dwelling older adults with knee pain.
Population-based, cross-sectional study of 745 adults aged 50 years and over with knee pain. Self-complete questionnaires, clinical history and physical examination were used to identify the presence of selected NACs that could cause pain around the knee. Regression analyses were used to compare levels of knee pain severity (0-20) and functional limitation (0-68) (Western Ontario and McMaster Universities osteoarthritis index physical function subscale [WOMAC-PF]), between those with one or more NACs and those with none (NACs-absent).
Two hundred and seventy-three (36.6%) participants had at least one NAC: widespread pain, n=159; low back pain with index leg referral, n=102; full-leg pain, n=88; hip arthritis, n=65; prepatellar, infrapatellar or pes anserine bursitis, n=35. The NACs group had significantly higher levels of pain severity and functional limitation than the NACs-absent group: 8.2(+/-4.6) vs 5.4(+/-3.8) and 27.9(+/-15.8) vs 16.8(+/-13.2), respectively. The groups did not differ with respect to severity of radiographic osteoarthritis (ROA). Having one or more NACs accounted for a significant proportion of the variance in WOMAC scores, above that which could be explained by age, gender, body mass index and severity of ROA.
NACs appear to be common in older adults with knee pain. They make a significant contribution to knee pain severity and functional limitation and are likely to represent additional, rather than alternative, causes of knee pain/functional limitation to osteoarthritis (OA). These factors should be taken into account in epidemiological studies of knee pain and OA.
评估特定非关节疾病(NACs)对社区居住的膝关节疼痛老年人疼痛严重程度和功能受限的影响。
基于人群的横断面研究,纳入745名年龄在50岁及以上的膝关节疼痛成年人。采用自我填写问卷、临床病史和体格检查来确定是否存在可能导致膝关节周围疼痛的特定NACs。使用回归分析比较有一个或多个NACs的人群与无NACs(无NACs组)人群之间的膝关节疼痛严重程度(0 - 20)和功能受限程度(0 - 68)(西安大略和麦克马斯特大学骨关节炎指数身体功能子量表[WOMAC - PF])。
273名(36.6%)参与者至少有一种NAC:广泛性疼痛,n = 159;伴有患侧下肢牵涉痛的腰痛,n = 102;全腿痛,n = 88;髋关节炎,n = 65;髌前、髌下或鹅足滑囊炎,n = 35。NACs组的疼痛严重程度和功能受限水平显著高于无NACs组:分别为8.2(±4.6)对5.4(±3.8)以及27.9(±15.8)对16.8(±13.2)。两组在放射学骨关节炎(ROA)严重程度方面无差异。有一个或多个NACs占WOMAC评分方差中的很大比例,超出了年龄、性别、体重指数和ROA严重程度所能解释的范围。
NACs在膝关节疼痛的老年人中似乎很常见。它们对膝关节疼痛严重程度和功能受限有显著影响,并且可能是膝关节疼痛/功能受限的额外原因,而非骨关节炎(OA)的替代原因。在膝关节疼痛和OA的流行病学研究中应考虑这些因素。