Valham Fredrik, Stegmayr Birgitta, Eriksson Marie, Hägg Erik, Lindberg Eva, Franklin Karl A
Department of Respiratory Medicine, University Hospital, Umeå, Sweden.
Sleep Med. 2009 Jan;10(1):112-7. doi: 10.1016/j.sleep.2007.11.005. Epub 2008 Jan 22.
Gender differences in the relationship of snoring and diabetes mellitus are mainly unknown. We aimed to analyze the relationship between snoring, witnessed sleep apnea and diabetes mellitus and to analyze possible gender related differences in an unselected population.
Questions on snoring and witnessed sleep apneas were included in the Northern Sweden component of the WHO, MONICA study. Invited were 10,756 men and women aged 25-79 years, randomly selected from the population register.
There were 7905 (73%) subjects, 4047 women and 3858 men who responded to the questionnaire and attended a visit for a physical examination. Habitual snoring was related to diabetes mellitus in women, with an adjusted odds ratio (OR)=1.58 (95% confidence interval (CI) 1.02-2.44, p=0.041) independent of smoking, age, body mass index and waist circumference. Witnessed sleep apnea was also independently related to diabetes mellitus in women, with an adjusted OR=3.29 (95% CI 1.20-8.32, p=0.012). Neither snoring, nor witnessed sleep apneas were associated with diabetes mellitus among men, except for witnessed sleep apnea in men aged 25-54 years old. They had an adjusted OR=3.84 (95% CI 1.36-10.9, p=0.011) for diabetes mellitus.
Snoring and witnessed sleep apneas are related to diabetes mellitus in women. Witnessed sleep apnea is related to diabetes mellitus in men younger than 55 years old.
打鼾与糖尿病之间的性别差异主要尚不清楚。我们旨在分析打鼾、目击性睡眠呼吸暂停与糖尿病之间的关系，并分析在未经过筛选的人群中可能存在的性别相关差异。
世界卫生组织MONICA研究瑞典北部部分纳入了有关打鼾和目击性睡眠呼吸暂停的问题。从人口登记册中随机选取了10756名年龄在25 - 79岁之间的男性和女性。
有7905名（73%）受试者，4047名女性和3858名男性回复了问卷并参加了体检。习惯性打鼾与女性糖尿病相关，校正优势比（OR）=1.58（95%置信区间（CI）1.02 - 2.44，p = 0.041），独立于吸烟、年龄、体重指数和腰围。目击性睡眠呼吸暂停也与女性糖尿病独立相关，校正OR = 3.29（95% CI 1.20 - 8.32，p = 0.012）。在男性中，除了25 - 54岁男性的目击性睡眠呼吸暂停外，打鼾和目击性睡眠呼吸暂停均与糖尿病无关。他们患糖尿病的校正OR = 3.84（95% CI 1.36 - 10.9，p = 0.011）。
打鼾和目击性睡眠呼吸暂停与女性糖尿病相关。目击性睡眠呼吸暂停与55岁以下男性的糖尿病相关。
