Yuan Yun, Zhang Fan, Qiu Jingfu, Chen Liling, Xiao Meng, Tang Wenge, Luo Qinwen, Ding Xianbin, Tang Xiaojun
School of Public Health and Management, Medical and Social Development Research Center, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Chongqing Municipal Center for Disease Control and Prevention, Chongqing, 400042, People's Republic of China.
Int J Gen Med. 2022 Mar 4;15:2491-2499. doi: 10.2147/IJGM.S352593. eCollection 2022.
To examine the relationship between diabetes and snoring frequency and determine the effect of menopause and postmenopausal years on this relationship.
We included 12,218 premenopausal and postmenopausal women from part of the baseline of the China Multi-Ethnic Cohort study (CMEC) in Chongqing province. Face-to-face questionnaires, physical examination, and biological samples were used to collect data. Logistic regression and subgroup analysis were used to explore the relationship between snoring and diabetes in women with various menopausal statuses.
The risk of diabetes increased with the snoring frequency, with adjusted odds ratios of 1.23 (95% CI:1.05-1.43) and 1.47 (95% CI:1.25-1.73) for sometimes snoring and frequent snoring, compared to non-snoring. In premenopausal and postmenopausal women, frequent snoring increased the odds of diabetes by 58% (95% CI: 7-132%) and 43% (95% CI: 20-72%), respectively, compared to non-snoring. Only in women who were ≥10 years postmenopausal had a statistical association between frequent snoring and diabetes, with a 54% (95% CI: 23-92%) increased odds of diabetes, compared to women who did not snore.
Snoring frequency is positively associated with diabetes. Women who snore frequently before and for at least ten years after menopause are at higher risk of developing diabetes. Frequent snorers and long-term postmenopausal women should monitor blood glucose levels to aid in the early detection and treatment of diabetes.
研究糖尿病与打鼾频率之间的关系，并确定绝经及绝经年限对这种关系的影响。
我们纳入了来自中国多民族队列研究（CMEC）重庆部分基线的12218名绝经前和绝经后女性。通过面对面问卷调查、体格检查和生物样本收集数据。采用逻辑回归和亚组分析探讨不同绝经状态女性打鼾与糖尿病之间的关系。
糖尿病风险随打鼾频率增加而升高，与不打鼾者相比，有时打鼾和频繁打鼾的校正比值比分别为1.23（95%CI：1.05 - 1.43）和1.47（95%CI：1.25 - 1.73）。在绝经前和绝经后女性中，与不打鼾者相比，频繁打鼾使糖尿病发生几率分别增加58%（95%CI：7 - 132%）和43%（95%CI：20 - 72%）。仅在绝经≥10年的女性中，频繁打鼾与糖尿病之间存在统计学关联，与不打鼾女性相比，糖尿病发生几率增加54%（95%CI：23 - 92%）。
打鼾频率与糖尿病呈正相关。绝经前及绝经后至少十年频繁打鼾的女性患糖尿病风险更高。频繁打鼾者及绝经后长期女性应监测血糖水平，以助于糖尿病的早期发现和治疗。
