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[炙甘草(制甘草)注射液的实验性抗心律失常作用]

[Experimental anti-arrhythmic effects of zhigancao (prepared licorice) injection].

作者信息

Chen R, Yuan C

机构信息

Longhua Hospital, Shanghai College of Traditional Chinese Medicine.

出版信息

Zhongguo Zhong Yao Za Zhi. 1991 Oct;16(10):617-9, inside back cover.

PMID:1820795
Abstract

Zhigancao injection can antagonise the arrhythmia induced by chloroform, adrenaline, aconitine, strophanthine K and barium chloride, slow the heart rate, prolong P-R and Q-T intervals and antagonise the positive chronotropic response induced by isoprenaline. The LD50 of zhigancao injection is 41.2g/kg in nice by intraperitoneal.

摘要

炙甘草注射液能对抗氯仿、肾上腺素、乌头碱、毒毛花苷K和氯化钡诱发的心律失常,减慢心率,延长P-R和Q-T间期,并对抗异丙肾上腺素引起的正性变时反应。炙甘草注射液腹腔注射对小鼠的半数致死量为41.2g/kg。

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