Sanchez A, Ygartua P, Fos D
Departamento de Farmacia y Tecnologia Farmaceutica, Facultad de Farmacia, Universidad de Navarra, Spain.
Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:120-4.
The nasal mucosa has good physiological characteristics to allow the administration through other routes presents some problems, such is the case of insulin. The presence of surfactants is necessary to get high bioavailability.
鼻黏膜具有良好的生理特性,可用于其他给药途径,但也存在一些问题,胰岛素就是这种情况。为了获得高生物利用度,表面活性剂的存在是必要的。