Wong Kevin K, Finlay Jane C, Moxham J Paul
Department of Surgery and Infectious , British Columbia's Children's Hospital, Vancouver, British Columbia, Canada.
Arch Otolaryngol Head Neck Surg. 2008 Jan;134(1):16-9. doi: 10.1001/archoto.2007.15.
To examine the efficacy of tonsillectomy in ameliorating symptoms and preventing recurrence of episodes in children with PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and adenitis).
Retrospective case series.
Tertiary care children's hospital.
Patients who presented to a major tertiary teaching hospital in Vancouver, British Columbia, Canada, between 2000 and 2004 with the diagnosis of PFAPA syndrome or for whom the diagnosis was made on their initial consultation.
Tonsillectomy.
Resolution of symptoms at 3, 12, and 24 months after tonsillectomy.
Eight of the 9 patients achieved complete remission within 3 months. In the remaining patient, the frequency of episodes decreased from every 2 weeks to once every 3 to 4 months. This patient eventually had resolution of symptoms at 2 years after tonsillectomy. No complications resulted from the tonsillectomy.
Tonsillectomy is a viable treatment option for patients with PFAPA syndrome.
探讨扁桃体切除术对改善周期性发热、口疮性口炎、咽炎和腺炎综合征（PFAPA综合征）患儿症状及预防发作复发的疗效。
回顾性病例系列研究。
三级医疗儿童医院。
2000年至2004年间就诊于加拿大不列颠哥伦比亚省温哥华一家大型三级教学医院，诊断为PFAPA综合征或初诊时确诊的患者。
扁桃体切除术。
扁桃体切除术后3个月、12个月和24个月时症状的缓解情况。
9例患者中有8例在3个月内实现完全缓解。其余1例患者发作频率从每2周一次降至每3至4个月一次。该患者最终在扁桃体切除术后2年症状得到缓解。扁桃体切除术未引发并发症。
扁桃体切除术是PFAPA综合征患者的一种可行治疗选择。
