Neau B, Damaj I, Lambrey B, Akbaraly J P, Roux J, Perrissoud D, Jacquot J
Centre de Recherche, Laboratories Sorget, Mérignac, France.
Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:77-9.
COR3224 is a new 2-amino-2 oxazoline derivative with antidepressant properties. The distribution, excretion and metabolism of radiochemically labelled 14C-COR3224 has been investigated in the rat after intravenous injection. The compound was widely distributed and rapidly excreted. Hydroxylation and sulphate conjugation are involved in the COR3224 elimination.
