Bellani A E, Rodolà F, Cannelli G, Barbi S
Università Cattolica del Sacro Cuore, Roma.
Riv Eur Sci Med Farmacol. 1991 May-Aug;13(3-4):137-9.
The authors report two cases of postanesthetic delirium in patients receiving intravenous atropine sulphate before surgery. In the first case the diagnosis of atropinic syndrome has been suggested by a cause effect relationship; in the second case the diagnosis has been supported by the prompt resolution after intravenous physostigmine salycilate administration. Since such syndrome was never observed in patients receiving atropine sulphate as i.m. premedicant, authors are prone to consider the i.m. route a safer approach to premedication with this drug.
作者报告了两例在手术前接受静脉注射硫酸阿托品的患者出现麻醉后谵妄的病例。在第一例中，通过因果关系提示了阿托品综合征的诊断；在第二例中，静脉注射水杨酸毒扁豆碱后症状迅速缓解支持了该诊断。由于在接受硫酸阿托品作为肌肉注射术前用药的患者中从未观察到这种综合征，作者倾向于认为肌肉注射途径是使用该药物进行术前用药的更安全方法。
