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阿托品术前用药继发的术后谵妄

Postoperative delirium secondary to atropine premedication.

作者信息

Hammon K, DeMartino B K

出版信息

Anesth Prog. 1985 May-Jun;32(3):107-8.

Abstract

Anticholinergic agents used as preoperative medications have the ability to induce postanesthetic delirium reactions. We present a case of postanesthetic delirium secondary to premedication with atropine which was treated with intravenous physostigmine. This case is presented to alert the clinician to the possibility of this reaction occurring with the use of atropine, and to demonstrate the use of physostigmine in reversing postanesthetic delirium reactions caused by anticholinergics.

摘要

用作术前用药的抗胆碱能药物有诱发麻醉后谵妄反应的能力。我们报告一例因术前使用阿托品导致麻醉后谵妄,经静脉注射毒扁豆碱治疗的病例。呈现此病例是为了提醒临床医生使用阿托品时可能发生这种反应,并展示毒扁豆碱在逆转抗胆碱能药物引起的麻醉后谵妄反应中的应用。

引用本文的文献

本文引用的文献

2
A comparison of atropine and glycopyrrolate in anaesthetic practice.
Acta Anaesthesiol Scand. 1982 Dec;26(6):620-5. doi: 10.1111/j.1399-6576.1982.tb01827.x.
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The treatment of scopolamine-induced delirium with physostigmine.
Clin Pharmacol Ther. 1967 May-Jun;8(3):409-14. doi: 10.1002/cpt196783409.
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Reversal of systemic toxic effects of scopolamine with physostigmine salicylate.
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The reversal of anticholinergic drug-induced delirium and coma with physostigmine.
Am J Psychiatry. 1971 Feb;127(8):1050-4. doi: 10.1176/ajp.127.8.1050.
10

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