Mimura Masaru
Department of Neuropsychiatry, Showa University School of Medicine.
Rinsho Shinkeigaku. 2007 Nov;47(11):865-7.
The "higher brain dysfunction" illustrates various cognitive and behavioral consequences resulted from organic brain damage. Individually-tailored cognitive rehabilitation aims to directly and explicitly ameliorate disability of people with higher brain dysfunction. In this symposium, the efficacy and limitation of cognitive rehabilitation was discussed with particular interest in the two cognitive domains, i.e., language and memory. In the realm of aphasia rehabilitation, two mechanisms have been postulated for language restitution following aphasia: 1) partial recovery of left-hemisphere language-related areas, and 2) activation of their homologous counterparts in the right hemisphere. Although the both hemispheres may eventually contribute for functional reorganization of the language network, recent functional imaging studies of aphasic patients have demonstrated that the residual left hemisphere is primarily important for aphasia recovery. A recently presented hypothesis was described in which suppressing the right hemisphere may lead to better aphasia recovery. It is now widely accepted in the field of memory rehabilitation for individuals with amnesia/dementia that the theoretical framework of "errorless learning" is a guiding principle. Error elimination during learning is essential for favorable outcome of memory training. We should be aware of functional organization of the brain which underlies the efficacy of cognitive rehabilitation.
“高级脑功能障碍”表现出由器质性脑损伤导致的各种认知和行为后果。个性化认知康复旨在直接且明确地改善高级脑功能障碍患者的残疾状况。在本次研讨会上,对认知康复的疗效和局限性进行了讨论,特别关注语言和记忆这两个认知领域。在失语症康复领域,针对失语症后语言恢复提出了两种机制:1)左半球与语言相关区域的部分恢复,以及2)右半球同源区域的激活。尽管两个半球最终都可能对语言网络的功能重组有所贡献,但近期对失语症患者的功能成像研究表明,残留的左半球对失语症恢复至关重要。描述了一个最近提出的假说,即抑制右半球可能导致更好的失语症恢复。在失忆症/痴呆症患者的记忆康复领域,“无错误学习”的理论框架作为指导原则现已被广泛接受。学习过程中的错误消除对于记忆训练的良好结果至关重要。我们应该了解作为认知康复疗效基础的大脑功能组织。