Safwenberg Urban, Terént Andreas, Lind Lars
Department of Medicine, Uppsala University Hospital, Uppsala, Sweden.
Acad Emerg Med. 2008 Jan;15(1):9-16. doi: 10.1111/j.1553-2712.2007.00004.x.
To characterize long-term mortality based on previous emergency department (ED) presenting complaints.
The authors followed, for 10 years, all of the 12,667 nonsurgical patients visiting an ED during 1995/1996. Differences in standardized mortality ratio (SMR) depending on presenting complaints were then investigated.
During follow-up, 5,324 deaths occurred (mortality rate 6.6 per 100 person-years at risk), giving a SMR of 1.33 (95% CI = 1.30 to 1.37, p < 0.001) when compared with the expected mortality in the catchment area. Different presenting complaints were associated with different long-term mortality rates, independent of age and gender (p < 0.0001). The subjects with seizures had the highest SMR (2.62, 95% CI = 2.13 to 3.22) followed by intoxications (2.51, 95% CI = 2.11 to 2.98), asthmalike symptoms (1.84, 95% CI = 1.65 to 2.06), and hyperglycemia (1.67, 95% CI = 1.42 to 1.95). The largest complaint group, chest pain, had a 20% higher mortality rate than the background population (95% CI = 1.13 to 1.26). Patients with a discharge diagnosis of myocardial infarction, but without chest pain as the presenting complaint, had an increased long-term mortality (hazard ratio [HR] 1.70, 95% CI = 1.15 to 2.42) compared to the group with chest pain. In contrast, stroke patients without strokelike symptoms had a reduced mortality (HR 0.74, 95% CI = 0.65 to 0.84) compared to patients with strokelike symptoms.
Long-term age- and gender-adjusted mortality is the highest with seizures out of 33 presenting complaints and differs markedly between different ED admission complaints. Furthermore, depending on the admission complaint, long-term mortality differs within the same discharge diagnosis. Hence, the presenting complaint adds unique information to the discharge diagnosis regarding long-term mortality in nonsurgical patients.
根据之前急诊科就诊时的主诉来描述长期死亡率情况。
作者对1995/1996年间前往某急诊科就诊的12667例非手术患者进行了为期10年的随访。然后调查了根据主诉不同的标准化死亡率(SMR)差异。
随访期间,发生了5324例死亡(风险人群中死亡率为每100人年6.6例),与集水区预期死亡率相比,标准化死亡率为1.33(95%可信区间=1.30至1.37,p<0.001)。不同的主诉与不同的长期死亡率相关,与年龄和性别无关(p<0.0001)。癫痫发作患者的标准化死亡率最高(2.62,95%可信区间=2.13至3.22),其次是中毒(2.51,95%可信区间=2.11至2.98)、哮喘样症状(1.84,95%可信区间=1.65至2.06)和高血糖(1.67,95%可信区间=1.42至1.95)。最大的主诉组胸痛,其死亡率比总体人群高20%(95%可信区间=1.13至1.26)。出院诊断为心肌梗死但就诊时无胸痛主诉的患者,与有胸痛主诉的组相比,长期死亡率增加(风险比[HR]1.70,95%可信区间=1.15至2.42)。相比之下,无中风样症状的中风患者与有中风样症状的患者相比,死亡率降低(HR 0.74,95%可信区间=0.65至0.84)。
在33种就诊主诉中,癫痫发作导致的长期年龄和性别调整死亡率最高,且不同急诊科入院主诉之间存在显著差异。此外,根据入院主诉,同一出院诊断内的长期死亡率也有所不同。因此,就诊主诉为非手术患者的长期死亡率出院诊断增加了独特信息。