慢性广泛性牙周炎的免疫学。2. 总溶血补体（CH50）及其C3和C4组分的测定。
Immunology of chronic generalized periodontitis. 2. Estimation of total hemolytic complement (CH 50) and its fractions C3 and C4.
作者信息
Anil S, Beena V T, Remani P, Haseenabeevi M, Vijayakumar T
机构信息
Department of Periodontics, Dental College, Trivandrum.
出版信息
Indian J Dent Res. 1991 Jul-Dec;2(3-4):35-9.
The total hemolytic complement activity (CH50) and its fractions C3 and C4 were determined in forty patients with chronic generalized periodontitis (CGP). The values were compared with an equal number of age and sex matched periodontally healthy controls. Total hemolytic complement activity was expressed as number of CH50 units per ml of blood, while C3 and C4 levels were assessed by radial immunodiffusion and expressed as mg%. The observations showed a significant increase in CH50, C3 and C4 levels in the sera of patients with CGP. The study reveals the role of complement system in the pathogenesis of chronic generalized periodontitis.
测定了40例慢性广泛性牙周炎（CGP）患者的总溶血补体活性（CH50）及其组分C3和C4。将这些值与同等数量的年龄和性别匹配的牙周健康对照者进行比较。总溶血补体活性以每毫升血液中CH50单位数表示，而C3和C4水平通过放射免疫扩散法评估并以mg%表示。观察结果显示，CGP患者血清中的CH50、C3和C4水平显著升高。该研究揭示了补体系统在慢性广泛性牙周炎发病机制中的作用。
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