Lamproye A, Belaiche J, Delwaide J
CHU Sart Tilman, Liège, Belgique.
Rev Med Liege. 2007;62 Spec No:68-72.
The FibroScan is a device allowing a non invasive diagnosis and quantification of liver fibrosis. The procedure is based on transient elastography and allows to record liver stiffness by measuring the velocity of shear wave across liver parenchyma. The elasticity is directly correlated to velocity of the wave. In chronic hepatitis C, there is a good correlation between liver elasticity and stage of fibrosis. The FibroScan has also been studied in other chronic liver diseases, such as hepatitis B, primary biliary cirrhosis, sclerosing cholangitis, auto-immune hepatitis, alcohol, steatosis, hemachromatosis with reproductible results. In a cirrhotic patient, it also allows to assess the severity of cirrhosis and to evaluate the risk of complication. It is a painless procedure, with a good acceptability by the patients. Therefore, the FibroScan can be regularly performed, allowing the follow up of fibrosis evolution over time.
FibroScan是一种可进行肝纤维化无创诊断和定量分析的设备。该检查基于瞬时弹性成像技术,通过测量剪切波在肝实质中的传播速度来记录肝脏硬度。弹性与波速直接相关。在慢性丙型肝炎中,肝脏弹性与纤维化程度之间存在良好的相关性。FibroScan也已在其他慢性肝病中进行研究,如乙型肝炎、原发性胆汁性肝硬化、硬化性胆管炎、自身免疫性肝炎、酒精性肝病、脂肪变性、血色素沉着症,均取得了可重复的结果。对于肝硬化患者,它还可以评估肝硬化的严重程度并评估并发症风险。这是一种无痛检查,患者接受度良好。因此,可以定期进行FibroScan检查,以便随时间追踪纤维化的进展情况。