Centre d'Investigation de la Fibrose hépatique, Hôpital Haut-Lévêque, 33604 Pessac Cedex, France.
Expert Rev Med Devices. 2010 Nov;7(6):811-23. doi: 10.1586/erd.10.46.
Transient elastography (FibroScan(®)) is a noninvasive method proposed for the assessment of liver fibrosis in patients with chronic liver diseases by measuring liver stiffness. It can be easily performed at the bedside or in the outpatient clinic with immediate results and good reproducibility. FibroScan is validated for the diagnosis of significant fibrosis and cirrhosis in chronic hepatitis C, in recurrence of hepatitis C after liver transplantation, in co-infected HIV-HCV patients, in chronic hepatitis B, in chronic cholestatic diseases, in alcoholic disease and in nonalcoholic fatty liver disease. FibroScan is an excellent tool for the early detection of cirrhosis and for the evaluation of portal hypertension, and may have prognostic value in this setting. FibroScan evaluates liver stiffness, which is related to fibrosis, but also inflammation and portal hypertension. Therefore, FibroScan values have to be interpreted according to clinical, biological and morphological data.
瞬时弹性成像（FibroScan(®)）是一种非侵入性方法，通过测量肝脏硬度来评估慢性肝病患者的肝纤维化。它可以在床边或门诊轻松进行，结果即刻得出，且重复性良好。FibroScan 已在慢性丙型肝炎的显著纤维化和肝硬化诊断、肝移植后丙型肝炎复发、HIV-HCV 合并感染患者、慢性乙型肝炎、慢性胆汁淤积性疾病、酒精性疾病和非酒精性脂肪性肝病中得到验证。FibroScan 是早期发现肝硬化和评估门静脉高压的优秀工具，在这种情况下可能具有预后价值。FibroScan 评估肝脏硬度，其与纤维化有关，但也与炎症和门静脉高压有关。因此，必须根据临床、生物学和形态学数据来解释 FibroScan 值。
