Chaudhuri K R, Thomaides T, Hernandez P, Alam M, Mathias C J
Department of Medicine, St Mary's Hospital Medical School, London, UK.
Clin Auton Res. 1991 Mar;1(1):37-42. doi: 10.1007/BF01826056.
The role of the splanchnic circulation in normal subjects during sympathoneural activation induced by stimuli which either raise (mental arithmetic, cold pressor test, isometric exercise) or maintain (head-up tilt) blood pressure has been studied by measuring superior mesenteric artery blood flow using a noninvasive Doppler ultrasound method in 18 normal subjects. Cardiac, systemic and regional haemodynamic changes were simultaneously studied. Blood pressure rose with the pressor tests and was maintained with head-up tilt. There was a significant fall in superior mesenteric artery blood flow with a rise in vascular resistance during each stimulus indicating active constriction. In six subjects, after 2 months measurements were repeated in an identical study. Superior mesenteric artery blood flow measurements in this study were closely correlated with the initial results. These changes, in a large vascular bed, are likely to be of importance in the overall haemodynamic response during sympathoneural stimuli which either raise or maintain blood pressure.
通过使用无创多普勒超声方法测量18名正常受试者的肠系膜上动脉血流，研究了在内脏循环在由升高（心算、冷加压试验、等长运动）或维持（头高位倾斜）血压的刺激所诱发的交感神经激活过程中，在正常受试者中的作用。同时研究了心脏、全身和局部血流动力学变化。血压在升压试验时升高，并通过头高位倾斜得以维持。在每种刺激过程中，肠系膜上动脉血流显著下降，血管阻力升高，表明存在主动收缩。在6名受试者中，2个月后在相同研究中重复测量。本研究中肠系膜上动脉血流测量结果与初始结果密切相关。在一个大血管床中的这些变化，在交感神经刺激过程中升高或维持血压时的整体血流动力学反应中可能具有重要意义。
