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生长锥运动性

Growth cone motility.

作者信息

Heidemann S R, Buxbaum R E

机构信息

Department of Physiology, Michigan State University, East Lansing 48824-1101.

出版信息

Curr Opin Neurobiol. 1991 Oct;1(3):339-45. doi: 10.1016/0959-4388(91)90050-h.

DOI:10.1016/0959-4388(91)90050-h
PMID:1821675
Abstract

The exact nature of growth cone motility is far from understood but progress has been made in several areas. It now appears that growth cones pull and not push; we will review the biophysical basis of growth cone movement. Current ideas on the regulation of growth cone motility and the relationship between motility and axon pathfinding are also discussed.

摘要

生长锥运动的确切本质远未被理解,但在几个领域已取得了进展。现在看来,生长锥是拉动而非推动;我们将回顾生长锥运动的生物物理基础。还将讨论当前关于生长锥运动调节以及运动与轴突导向之间关系的观点。

相似文献

1
Growth cone motility.生长锥运动性
Curr Opin Neurobiol. 1991 Oct;1(3):339-45. doi: 10.1016/0959-4388(91)90050-h.
2
The cytoskeleton in nerve growth cone motility and axonal pathfinding.细胞骨架在神经生长锥运动和轴突导向中的作用
Perspect Dev Neurobiol. 1996;4(2-3):111-23.
3
Directional guidance of nerve growth cones.神经生长锥的定向引导
Curr Opin Neurobiol. 2006 Feb;16(1):52-8. doi: 10.1016/j.conb.2005.12.005. Epub 2006 Jan 4.
4
The neuronal growth cone: a review of its locomotory, navigational and target recognition capabilities.神经元生长锥:其运动、导航及靶标识别能力综述
Neuroscience. 1987 Mar;20(3):719-29. doi: 10.1016/0306-4522(87)90235-1.
5
The unique and shared properties of neuronal growth cones that enable navigation and specific pathfinding.神经生长锥的独特和共同特性使其能够进行导航和特定的路径寻找。
J Physiol Paris. 1994;88(3):155-63. doi: 10.1016/0928-4257(94)90001-9.
6
Glial cell extracellular matrix: boundaries for axon growth in development and regeneration.胶质细胞外基质:发育和再生中轴突生长的边界
Cell Tissue Res. 1997 Nov;290(2):379-84. doi: 10.1007/s004410050944.
7
Molecular mechanisms of directed growth cone motility.
Perspect Dev Neurobiol. 1996;4(2-3):137-45.
8
The region-specific activities of lipid rafts during axon growth and guidance.脂筏在轴突生长和导向过程中的区域特异性活动。
J Neurochem. 2006 Jul;98(2):330-5. doi: 10.1111/j.1471-4159.2006.03888.x.
9
The role of microtubule dynamics in growth cone motility and axonal growth.微管动力学在生长锥运动性和轴突生长中的作用。
J Cell Biol. 1995 Jan;128(1-2):139-55. doi: 10.1083/jcb.128.1.139.
10
In vivo regulation of axon extension and pathfinding by growth-cone calcium transients.生长锥钙瞬变对轴突延伸和路径寻找的体内调节。
Nature. 1999 Jan 28;397(6717):350-5. doi: 10.1038/16927.

引用本文的文献

1
Cellular strategies of axonal pathfinding.轴突导向的细胞策略。
Cold Spring Harb Perspect Biol. 2010 Sep;2(9):a001933. doi: 10.1101/cshperspect.a001933. Epub 2010 Jun 30.
2
Tumor cell motility and metastasis : Autocrine motility factor as an example of ecto/exoenzyme cytokines.肿瘤细胞的迁移和转移:以自分泌运动因子为例的细胞外酶细胞因子。
Pathol Oncol Res. 1997 Sep;3(3):230-54. doi: 10.1007/BF02899927.
3
Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid.
Rho家族小G蛋白与神经元生长锥重塑:Cdc42Hs、Rac1和乙酰胆碱诱导的复杂性增加与RhoA和溶血磷脂酸诱导的塌陷之间的关系。
Mol Cell Biol. 1997 Mar;17(3):1201-11. doi: 10.1128/MCB.17.3.1201.
4
The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts.Ras相关蛋白Cdc42Hs和缓激肽促进瑞士3T3成纤维细胞中外周肌动蛋白微刺和丝状伪足的形成。
Mol Cell Biol. 1995 Apr;15(4):1942-52. doi: 10.1128/MCB.15.4.1942.