Terskikh V V, Vasil'ev A V, Voroteliak E A
Tsitologiia. 2007;49(11):933-8.
Asymmetric cell division observed in many groups of organisms has similar mechanisms suggesting conservatism of the process. Asymmetric division of stem cells that reside in their niches is aimed to regulation of cell proliferation and genome stability maintenance. But stem cells may also divide symmetrically depending on situation. Alteration of mechanisms of asymmetric division might be one of the factors of neoplasm growth.
在许多生物群体中观察到的不对称细胞分裂具有相似的机制，这表明该过程具有保守性。位于其微环境中的干细胞的不对称分裂旨在调节细胞增殖和维持基因组稳定性。但干细胞也可能根据情况进行对称分裂。不对称分裂机制的改变可能是肿瘤生长的因素之一。
