Keller D I
Medizinische Poliklinik und Klinik für Kardiologie, Universitätsspital Basel.
Praxis (Bern 1994). 2007 Dec 19;96(51-52):2041-6. doi: 10.1024/1661-8157.96.51.2041.
Performing sports regularly has many positive effects on the cardiovascular and other systems. The shade side of the sport (not only high-performance-, but also amateur sports) is sudden cardia death, a dramatic event for the patient and his family. Many cardiac disorders, which lead to sudden cardiac death, are inherited. One of the most common causes of sudden cardiac death is autosomal-dominant inherited hypertrophic cardiomyopathy characterized by its wide phenotype and genotype heterogeneity. This specific disease will be elucidated in this paper. In order to prevent sudden cardiac death in athletes, a structured cardiovascular screening is mandatory at the beginning of the sport career. If an inherited disorder leading to sudden cardiac death is diagnosed, family screening will be necessary.
定期进行体育活动对心血管及其他系统有诸多积极影响。体育运动的阴暗面（不仅是高水平运动，业余运动亦是如此）是心源性猝死，这对患者及其家人来说是一个悲剧性事件。许多导致心源性猝死的心脏疾病是遗传性的。心源性猝死最常见的原因之一是常染色体显性遗传性肥厚型心肌病，其具有广泛的表型和基因型异质性。本文将对这种特定疾病进行阐释。为预防运动员的心源性猝死，在运动生涯开始时进行结构化的心血管筛查是必不可少的。如果诊断出导致心源性猝死的遗传性疾病，那么对其家族进行筛查将很有必要。
