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以肺部肿块为表现的原发性单相滑膜肉瘤:一例报告

Primary monophasic synovial sarcoma presenting as a pulmonary mass: a case report.

作者信息

Mermigkis Charalampos M, Kopanakis Antony, Patentalakis George, Polychronopoulos Vlassis, Patentalakis Michael

机构信息

Third Pulmonary Department, Sismanoglio General District Hospital, Athens, Greece.

出版信息

J Med Case Rep. 2008 Jan 24;2:18. doi: 10.1186/1752-1947-2-18.

Abstract

INTRODUCTION

Primary pulmonary synovial sarcoma is an extremely rare tumor with only few case reports in the literature.

CASE PRESENTATION

A healthy 67-year-old woman was admitted for investigation of a pulmonary mass found on a routine X-ray. She had a history of breast cancer diagnosed and treated 13 years previously with left mastectomy followed by adjuvant endocrine therapy. No progression of the disease was reported. Thoracic computer tomography disclosed a soft-tissue mass in the lower lobe of the left lung arising in the vicinity of the pleura. No abnormal lymph nodes were noted. Further work-up for metastases was negative. Subsequently, the lower lobe of the left lung was removed and the diagnosis was a monophasic synovial sarcoma.

CONCLUSION

The diagnosis of monophasic primary pulmonary synovial sarcoma requires clinical, imaging and immunohistochemical investigation to exclude alternative primary sources. The treatment of choice is excision (lobectomy or pneumonectomy), which in most of cases is helpful for diagnosis. The prognosis is usually poor.

摘要

引言

原发性肺滑膜肉瘤是一种极为罕见的肿瘤,文献中仅有少数病例报告。

病例介绍

一名67岁健康女性因常规X线检查发现肺部肿块入院。她有13年前诊断并治疗乳腺癌的病史,接受了左乳房切除术及辅助内分泌治疗。未报告疾病进展情况。胸部计算机断层扫描显示左肺下叶胸膜附近有一个软组织肿块。未发现异常淋巴结。进一步的转移检查为阴性。随后,切除了左肺下叶,诊断为单相滑膜肉瘤。

结论

单相原发性肺滑膜肉瘤的诊断需要临床、影像学和免疫组化检查以排除其他原发性来源。首选治疗方法是切除(肺叶切除术或全肺切除术),这在大多数情况下有助于诊断。预后通常较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/973e/2249601/dc3706bed3a8/1752-1947-2-18-1.jpg

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