Walecka W, Habrat E
II Kliniki Psychiatrycznej Instytutu Psychiatrii i Neurologii.
Psychiatr Pol. 1991 May-Aug;25(3-4):90-5.
Studies performed on a group of 27 patients with endogenous depression demonstrated that changes of cognitive functions following sleep deprivation may reveal a prognostic potential for results of pharmacological treatment of depression. Worsening of memory following sleep deprivation was more frequently observed in a subgroup of nonresponders. Greater improvement of concentration and increased task mobilization were noticed in a subgroup which positively responded to the antidepressant treatment. Patient's age, sex, self-rating of depression intensity or baseline level of ability to memorize, to concentrate attention, to perform tasks did not exhibit any predictive value.
对一组27名内源性抑郁症患者进行的研究表明，睡眠剥夺后认知功能的变化可能揭示抑郁症药物治疗结果的预后潜力。在无反应者亚组中，睡眠剥夺后记忆力恶化的情况更常见。在对抗抑郁治疗有积极反应的亚组中，注意力集中度有更大改善，任务调动能力增强。患者的年龄、性别、抑郁强度自评或记忆、集中注意力、执行任务能力的基线水平均未显示出任何预测价值。
