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[动脉高血压神经源性决定因素研究中的人群模型。报告一。精神分裂症中动脉高血压的特点]

[Population models in the study of the neurogenic determinants of arterial hypertension. Report I. Peculiarities of arterial hypertension in schizophrenia].

作者信息

Tret'iakov A Iu, Zakharchenko S P, Smirnova O I, Khoshchenko Iu A, Grigorenko A L

出版信息

Klin Med (Mosk). 2007;85(11):31-6.

Abstract

In order to clarify the role of the central nervous system in the genesis of arterial hypertension (AH) a population analysis of somatic pathology in schizophrenia was performed. Using clinical and postmortem data, the study found lower frequency of AH among mental patients vs. somatic ones; primary AH was benign independently of the psychotropic therapy regimen. II to III stage AH in psychosis was associated with primary or secondary renal pathology or magistral vessel atherosclerosis. Severe schizophrenia and a pronounced personality defect were associated with low intensity of the primary form of somatic nosology.

摘要

为了阐明中枢神经系统在动脉高血压(AH)发病机制中的作用,对精神分裂症患者的躯体病理学进行了群体分析。利用临床和尸检数据,研究发现精神科患者中AH的发生率低于躯体疾病患者;原发性AH是良性的,与精神药物治疗方案无关。精神病患者的II至III期AH与原发性或继发性肾脏病理或主要血管动脉粥样硬化有关。严重精神分裂症和明显的人格缺陷与躯体疾病分类学原发性形式的低强度有关。

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