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Missing data and the trouble with LOCF.

作者信息

Streiner David L

机构信息

Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care and Professor, Department of Psychiatry, University of Toronto, Canada.

出版信息

Evid Based Ment Health. 2008 Feb;11(1):3-5. doi: 10.1136/ebmh.11.1.3-a.

DOI:10.1136/ebmh.11.1.3-a
PMID:18223040
Abstract
摘要

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Handling drop-out in longitudinal clinical trials: a comparison of the LOCF and MMRM approaches.纵向临床试验中失访情况的处理：末次观察结转（LOCF）与多重填补重复测量法（MMRM）方法的比较
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