Lancellotti P, Moonen M, Zacharakis D, Pierard L
Université de Liège, CHU Sart Tilman, Liège, Belgique.
Arch Mal Coeur Vaiss. 2007 Dec;100(12):1056-62.
Mitral regurgitation (MR) is a serious complication of coronary heart disease. The functional form is the most frequent, often presenting with a dynamic character. The presence, and in particular the severity of MR and its dynamic character have a major impact on the medium and long term prognosis. The mechanisms responsible for MR are complex and occur in a state of disequilibrium between traction forces and closing forces, for which the significance is partly affected by the presence of asynchrony in left ventricular contraction. The therapeutic management of these patients is difficult. In cases of proven asynchrony, implantation of a biventricular pacemaker is justified. A mitral surgical procedure may be envisaged in cases of severe MR where bypass surgery is planned. In cases of moderate MR at rest, an evaluation of its dynamic character on effort can assist with the decision to undertake combined surgery. Mitral regurgitation (MR) is a common and serious complication of ischemic heart disease. Three general forms are distinguished: MR related to acute rupture of the mitral pillar, ischemic MR and functional MR.
二尖瓣反流（MR）是冠心病的一种严重并发症。功能性二尖瓣反流最为常见，通常具有动态特征。二尖瓣反流的存在，尤其是其严重程度及其动态特征对中长期预后有重大影响。导致二尖瓣反流的机制很复杂，发生在牵拉力和闭合力失衡的状态下，其意义部分受左心室收缩不同步的影响。这些患者的治疗管理很困难。在已证实存在不同步的情况下，植入双心室起搏器是合理的。在计划进行搭桥手术的严重二尖瓣反流病例中，可以考虑进行二尖瓣外科手术。在静息时为中度二尖瓣反流的病例中，评估其运动时的动态特征有助于决定是否进行联合手术。二尖瓣反流（MR）是缺血性心脏病常见且严重的并发症。可分为三种一般类型：与二尖瓣乳头肌急性破裂相关的二尖瓣反流、缺血性二尖瓣反流和功能性二尖瓣反流。
