Iarkov S P, Tret'iakov S I, Basharova L A, Zlobin V N
Vestn Ross Akad Med Nauk. 2007(12):22-6.
The use of immunochromatographic indicatory elements based on antibody conjugates and colloidal gold was suggested to detect cells and the antigens of extremely dangerous infectious pathogens. The specificity and specific activity (sensitivity) of the mentioned elements were studied on vaccinal strains of plague, anthrax, and tularemia pathogens. The researchers studied a possibility to increase the sensitivity of immunochromatographic analysis using computed scanning and Reflecom, a specialized digital video recorder of immunochromatogramms. The study demonstrated that the use of electronic devices to record immunochromatogramms increased the sensitivity to microbial cells and antigens 1.5 to 2 times vs. visual registration and simplified documentation of the results.
有人建议使用基于抗体结合物和胶体金的免疫层析指示元件来检测细胞以及极其危险的传染性病原体的抗原。在鼠疫、炭疽和兔热病病原体的疫苗株上研究了上述元件的特异性和比活性(灵敏度)。研究人员研究了使用计算机扫描和Reflecom(一种免疫层析图专用数字视频记录仪)提高免疫层析分析灵敏度的可能性。该研究表明,与目视记录相比,使用电子设备记录免疫层析图可将对微生物细胞和抗原的灵敏度提高1.5至2倍,并简化了结果记录。