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胎儿心律失常的药物管理:我们是否准备好采用系统且基于证据的方法?

Drug management of fetal tachyarrhythmias: are we ready for a systematic and evidence-based approach?

作者信息

van den Heuvel Freek, Bink-Boelkens Margreet T H E, du Marchie Sarvaas Gideon J, Berger Rolf M F

机构信息

Department of Pediatric Cardiology, Beatrix Childrens Hospital, University Medical Center Groningen, University of Groningen, The Netherlands.

出版信息

Pacing Clin Electrophysiol. 2008 Feb;31 Suppl 1:S54-7. doi: 10.1111/j.1540-8159.2008.00958.x.

Abstract

Fetal tachyarrhythmias are a life-threatening condition complicating a small proportion of normal pregnancies. Despite major advances in the (intrauterine) pharmacologic treatment of these arrhythmias over the last years major uncertainties remain. Among these are controversies in the choice of agents in relation to arrhythmia type, and timing and duration of treatment. Currently, no evidence-based approach to the management of fetal tachyarrhythmias is available. An international registry is proposed as an important step toward obtaining the necessary data to develop evidence-based management strategies.

摘要

胎儿心律失常是一种危及生命的病症,在一小部分正常妊娠中会出现并发症。尽管在过去几年中,这些心律失常的(宫内)药物治疗取得了重大进展,但仍存在重大不确定性。其中包括在心律失常类型、治疗时机和持续时间方面药物选择的争议。目前,尚无基于证据的胎儿心律失常管理方法。提议建立一个国际登记处,作为获取必要数据以制定基于证据的管理策略的重要一步。

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