Trappe Hans-Joachim
Department of Cardiology and Angiology, Ruhr-University Bochum, Germany.
J Intensive Care Med. 2006 Sep-Oct;21(5):305-15. doi: 10.1177/0885066606291433.
Atrial premature beats are frequently diagnosed during pregnancy. Supraventricular tachycardia (atrial tachycardia, atrioventricular nodal reentrant tachycardia, circus movement tachycardia) is diagnosed less frequently. For acute therapy, electrical cardioversion with 50 to 100 J is indicated in all unstable patients. In stable supraventricular tachycardia, the initial therapy includes vagal maneuvers to terminate tachycardias. For short-term management, when vagal maneuvers fail, intravenous adenosine is the first choice drug and may safely terminate the arrhythmia. Ventricular premature beats are also frequently present during pregnancy and are benign in most patients; however, malignant ventricular tachyarrhythmias (sustained ventricular tachycardia, ventricular flutter, or ventricular fibrillation) may occur. Electrical cardioversion is necessary in all patients who are hemodynamically unstable with life-threatening ventricular tachyarrhythmias. In hemodynamically stable patients, initial therapy with ajmaline, procainamide, or lidocaine is indicated. In patients with syncopal ventricular tachycardia, ventricular fibrillation, ventricular flutter, or aborted sudden death, an implantable cardioverter-defibrillator is indicated. In patients with symptomatic bradycardia, a pacemaker can be implanted using echocardiography at any stage of pregnancy. The treatment of the pregnant patient with cardiac arrhythmias requires important modifications of the standard practice of arrhythmia management. The goal of therapy is to protect the patient and fetus through delivery, after which chronic or definitive therapy can be administered.
孕期常可诊断出房性早搏。室上性心动过速(房性心动过速、房室结折返性心动过速、环形运动性心动过速)的诊断则相对较少。对于急性治疗,所有不稳定患者均需采用50至100焦耳的电复律。对于稳定的室上性心动过速,初始治疗包括采用迷走神经手法来终止心动过速。对于短期处理,当迷走神经手法无效时,静脉注射腺苷是首选药物,且可能安全地终止心律失常。孕期也常出现室性早搏,且多数患者为良性;然而,可能会发生恶性室性心律失常(持续性室性心动过速、心室扑动或心室颤动)。对于所有因危及生命的室性心律失常而血流动力学不稳定的患者,均需进行电复律。对于血流动力学稳定的患者,初始治疗可选用阿义马林、普鲁卡因胺或利多卡因。对于发生晕厥性室性心动过速、心室颤动、心室扑动或心脏骤停的患者,建议植入植入式心脏复律除颤器。对于有症状性心动过缓的患者,在孕期的任何阶段均可使用超声心动图引导植入起搏器。对患有心律失常的孕妇进行治疗需要对心律失常管理的标准做法进行重要调整。治疗的目标是在分娩前保护患者和胎儿,分娩后再进行慢性或确定性治疗。